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Metaraminol is a sympathomimetic amine of both direct and indirect action that has hemo-dynamic characteristics similar to norepinephrine. It has the ability to elevate both systolic and diastolic blood pressure.

It is used in hypotensive shock for the purpose of elevating blood pressure, which can result from spinal anesthesia, surgical complications, and head trauma. Synonyms of metaraminol are aramine, isophenylephrin, metaradine, and others.

Amphetamines: The term amphetamines is usually used in relation to racemates of amphetamine, dextroamphetamine (8.1.2.2), and methamphetamine (8.1.2.3).

As drugs of mixed action, amphetamines activate adrenergic receptors and simultaneously release endogenic catecholamines (norepinephrine and dopamine) from neurons of the brain and periphery. Sympathomimetic effects on the periphery are very similar to those of ephedrine. Amphetamine elevates systolic and diastolic blood pressure and has weakly expressed, broncholytic action. These effects are more prolonged, yet less expressed, than with epinephrine. The distinctive feature of amphetamines is their psychostimulatory activity. Larger doses can cause hallucinations and mental conditions similar to paranoid schizophrenia. As a sympathomimetic, amphetamine is sometimes used for uterine inertia. Synonyms of amphetamine are phenamine and benzedrine.

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