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This drug lessens the allergic response of the organism caused by histamine. Tripelennamine is used for allergic symptoms, rhinitis, conjunctivitis, and for allergic and anaphylactic reactions. Synonyms of this drug are pelanin and pyribenzamine.

Pyrilamine: Pyrilamine, N-(4-methoxybenzyl)-W,N'-dimethyl-N-2-pyridilethylenedi-amine (16.1.7), is synthesized in the same manner, except using 2-(4-methoxybenzy-lamino)pyridine [10-12].

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Pyrilamine is also used for allergy symptoms and rhinitis. Synonyms of this drug are vis-tosan, anthisan, and triaminic.

Chloropyramine: Chloropyramine, N-(4-chlorobenzyl)-W,N'-dimethyl-N-2-pyridylethyl-enediamine (16.1.9), is synthesized in a somewhat different manner, which is by reacting 2-brompyridine with N-(4-chlorobenzyl)-W,N'-dimethylethylenediamine (16.1.8). N-(4-Chlorobenzyl)-N',N'-dimethylethylenediamine (16.1.8), in turn, is synthesized by condensation of 4-chlorobenzaldehyde c N,N-dimethylethylenediamine with subsequent reduction of the imine group [13-19].

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