This drug possesses a pronounced anticough effect and minimal action on the CNS. It is not addictive. Synonyms of this drug are coffex, robidex, seatuss, and others.

Benzonatate: Benzonatate, p-butylaminobenzoate 2,5,8,11,14,17,20,23,26-nonaocta-cozan-28-ol (23.2.2), is synthesized by reesterifying the ethyl ester of 4-butylaminoben-zoic acid with the monomethyl ether nonaethylenglycol. It is a structural analog of the local anesthetic tetracaine [3,4].

C4H9NH^^"^— COOC2H5 + HO-(CH2CH2O)9-CH3 -*■ C4H9NH^^~^— COO — (CH2CH2O)9-CH3

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