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Finally, a method of making medazepam from 4-chloro-N-methylaniline is suggested. The last is reacted with ethyleneimine in the presence of aluminum chloride, giving N-(4-chlorophenyl)-N-methylethylenediamine (5.1.43). Acylation of the resulting product with benzoyl chloride gives the respective amide (5.1.44), which cyclizes into the desired medazepam (5.1.40) using phosphorous oxychloride [44,45].

Various modifications of the described methods have been suggested [46,47]. Medazepam is a daytime tranquilizer. It exhibits an anxiolytic, myorelaxant, and anticonvulsant action. This drug relieves the feeling of worry, restores emotional calmness, and has a stabilizing effect on the vegetative nervous system. Medazepam is used in neurosis, psychopathy accompanied by excitement, stress, elevated irritability, insomnia, and functional neurosis of the cardiovascular system. Synonyms for this drug are nobrium, tranquirax, azepamid, and others.

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Do Not Panic

Do Not Panic

This guide Don't Panic has tips and additional information on what you should do when you are experiencing an anxiety or panic attack. With so much going on in the world today with taking care of your family, working full time, dealing with office politics and other things, you could experience a serious meltdown. All of these things could at one point cause you to stress out and snap.

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