Propranolol has been studied most carefully in experiments and in clinics. It is used for ventricular tachycardia, arrhythmia caused by digitalis drug overdose, or as a result of thy-rotoxosis or excess catecholamine activity. Despite the fact that there are a number of /¡-adrenoblockers, propranolol is considered the first choice of drugs although other blockers of calcium blockers can be just as effective.
Propranolol slows heart rate, increases the effective refractory period of atrioventricular ganglia, suppresses automatism of heart cells, and reduces excitability and contractibility of the myocardium. It is used for supraventricular and ventricular arrhythmias. Synonyms of this drug are anaprilin, detensiel, inderal, novapranol, and others.
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