Polonovski Rearrangement Lorazepam

Fuel Cell Anaesthesia

Oxazepam is similar to chlordiazepoxide in terms of pharmacological properties however, it has a somewhat less harsh effect, is less toxic, and exhibits a less expressed myorelaxant effect. It is often tolerated better by patients than other tranquilizers. It is used in neurosis, conditions of anxiety, fear, stress, trouble falling asleep, and psychovegatative disorders. The most common synonyms are nozepam and tazepam. Lorazepam Lorazepam, 5.1.31 , is synthesized according to a scheme...

Synthesis Of Norfloxacin

Norfloxacin Synthesis

Cinoxacin, Azolinic acid Cinoxacin, cinnolin-3-carboxylic acid 33.2.14 , is synthesized by a different scheme starting with 2-amino-4,5-methylendioxyacetophenone 33.2.10 , which is synthesized by reducing 4,5-methylendioxy-2-nitroacetophenone with hydrogen over a platinum catalyst. In diazo-tation conditions, this undergoes spontaneous heterocyclization to 4-hydroxy-6, 7-methylendioxycinnoline 33.2.11 obviously due to the presence of a significant amount of the enol form of acetophenone 33.2.10...

Tricyclic Antidepressants

The most frequently used drugs are tricyclic antidepressants, which received their name from the organization of their chemical structures, in particular the systems consisting of two benzene rings joined to a central 7-membered ring with a dialkylaminoalkyl group connected to the central ring. Depending on the substituents on the terminal nitrogen atom in the amine-containing side chain, they in turn are subdivided into tertiary imipramine, amitriptyline, trimipramine, doxepin and secondary...