Pemoline

Liver Limitations in post-marketing surveillance and public reporting in the USA, particularly in the 1980s, largely accounted for delays in ensuring an appropriate response to pemo-line hepatotoxicity (56R). Several authors have urged that voluntary reporting systems need augmentation (57R, 58r, 59R), including the addition of an active surveillance system to assess the prevalence of adverse drug reactions and the increased use of public health-oriented information sources to disseminate clearly documented drug risk information to physicians and their patients. The case of pemoline is just one example of this.

DRUGS USED IN ALZHEIMER'S DISEASE (SED-14, 435; SEDA-23, 8; SEDA-24, 6; SEDA-25, 7)

Cholinesterase inhibitors are currently the mainstay of treatment for mild-to-moderate

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