Recreational Drugs Manufacture

Extracting Or Separating These Substances

A thorough knowledge of the physical properties of the compounds in the medication that you are dealing with must be known. The Merck Index will have these substances listed along with their mp, bp, and solubilities. The best way to show you how this separation is effected is to give you some examples. Let's say that I just purchased 6 fl. oz. of average codeine cough syrup. I read the label and find that every fl. oz. contains 1000 mg times 6 6000 Pseudoephedrine mg times 6 360 mg mg times 6...

LSD Synthesis

As with the rest of this book, I will deal only with the synthetic manufacture of drugs (LSD included). If you want to grow the ergot alkaloids that begin the total synthesis of LSD, then you will have to go to the Merck Index and look up the references to the operation, Michael V. Smith's book, Psychedelic Chemistry, has a section on growing Claviceps purpurea, which yield ergot compounds. This section is very complete and informative, but I think that you should also look up the dangers of...

LSD From Ergot Alkaloids

This was invented by Hofmann and is a superior method because you may proceed from the ergot alkaloids to LSD without isolating the lysergic acid. CA, 57,12568 (1962). Add 1.2 g of ergotamine hydrochloride to 4 ml of anhydrous hydrazine and heat 1 hour at 90 . Add 20 ml of water and evaporate in vacuo, to get d-iso-lysergic acid hydrazine. 1 g of the lysergic hydrazine is powdered well and added to 40 ml of 0.1 N (ice cold) HC1 acid. To this, cooled to 0 , is added 4 ml of 1 N Na nitrite, with...