Pharmacology and toxicology
Polidocanol is used externally in cases of itching. In addition, it is used intravenously to obliterate varicose veins, for lesions of the mouth mucosa, in vaginal spermicides, and in cosmetics. Polidocanol in combination with benzethonium and carbamide (urea) has been applied in wound therapeutics. No teratogenic action has been observed to date, in either animal or human studies, for this widely used substance. However, there have been no systematic studies published.
Recommendation. Pregnant women may use polidocanol in cases of itching.
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