Mebendazole and flubendazole

Most infections of adults with common nematodes like ascaris and trichuris will be asymptomatic, and there is rarely an indication for treatment during pregnancy. Severe infections with hookworms may cause anemia, responsible, if during pregnancy, for increased perinatal mortality and morbidity worldwide. The WHO estimates that as many as 44 million pregnant women throughout the world are infected with hookworms (WHO 1996B). Mebendazole is a highly effective and well-tolerated drug against...

Gastritis and peptic ulcer during pregnancy

During prcgnancy, motility changes occur throughout the gastrointestinal tract. These changes are largely attributed to increased levels of progesterone and estrogen. The mechanisms promoting gastroesophageal reflux during gestation primarily involve decreased lower esophageal sphincter (LF.S) pressure and a decrease in the sphincter's adaptive responses, but mechanical factors may also be important. Gastroesophageal reflux and heartburn are common during pregnancy. In mild cases, lifestyle and...