Analysis of Phytocannabinoids

Instrumental methods are most often used for the identification, classification (e.g., fiber type, drug type), and individualization (e.g., source tracing) of Cannabis plants and products. Because of the complex chemistry of Cannabis, separation techniques, such as GC or liquid chromatography, often coupled with MS, are necessary for the acquisition of the typical chemical profiles and the sensitive, specific, qualitative, and/or quantitative (e.g., THC potency) determination of Cannabis constituents. However, especially for screening purposes and on-site field testing, noninstrumental techniques like thin-layer chromatography (TLC) and color reactions are helpful, too.

Table 8 Noncannabinoid Phenols

Compound

Structure

OR!

Ri = H, R2 = CH3

Isocannabispiran

Ri — CH3i R2 — H

Ri

oh rjf^

Cannabistilbene-I

Ri = OH, R2 = isoprenyl, R3 = H

Ri = OCHs, R2 = OH, R3 = OCHs

Cannabistilbene-ll

R1 = OCH3, R2 = OCH3, R3 = OH

och3

fll

ho >

Ri = H, R2 = OH

Cannithrene-2

Ri = OH, R2 = OCH3

0 0

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