Phencyclidine

PCP is one of the "NIDA five" drugs and is included in most workplace drug testing programs. For clinical drug testing, however, the prevalence of PCP abuse may be too low in some regions to justify routine testing for PCP. Immunoassays available for PCP include EMIT, FPIA, KIMS, and CEDIA. False-positive results have been reported due to interference by dextromethorphan (43), diphendyramine (44), and thioridazine (45). In view of the low prevalence of PCP abuse and the poor specificity of the immunoassay, one should expect that the test has low positive predictive value and most presumptive positive results by immunoassay are likely to be false positives. Therefore, it is important to confirm a PCP positive immunoassay result by another analytical technique.

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