A number of studies have shown the presence of opiates in oral fluid (67,73-75). The major opiates studied were codeine, morphine, hydrocodone, hydromorphone, 6-acetylmorphine and oxycodone. Jones et al. (30) described a GC-MS method for simultaneous measurement of these opiates in hair and oral fluid. When performing opiate assay, keto-opiates (hydrocodone, hydromorphone and oxycodone) pose special problems as they form multiple derivatives that interfere in analysis of other opiates and are difficult to quantitate. Oximization with hydroxylamine or methoxamine is used to overcome this problem (76). Singh et al. (77) used sodium bisulfite followed by solid-phase extraction to eliminate interference by keto-opiates in the analysis of opiates. Methadone which is extensively used in maintenance therapy of heroin addicts can also be detected in oral fluid.

Dealing With Asthma Naturally

Dealing With Asthma Naturally

Do You Suffer From ASTHMA Chronic asthma is a paralyzing, suffocating and socially isolating condition that can cause anxiety that can trigger even more attacks. Before you know it you are caught in a vicious cycle Put an end to the dependence on inhalers, buying expensive prescription drugs and avoidance of allergenic situations and animals. Get control of your life again and Deal With Asthma Naturally

Get My Free Ebook

Post a comment