Clinical Falsepositive Results

Many causes for clinical false-positive results have been published in the scientific literature or reported anecdotally. The most common causes can be grouped into four categories: (a) environmental exposure—passive inhalation or secondary smoke; (b) use of prescription medications containing the target drug(s); (c) use of prescription medications which are metabolized to the target drug(s); (d) consumption of food products which contain or are contaminated with the target drug(s). These reported causes and examples of the clinical false-positive results are listed in Table 1. In the following sections, clinical false-positive results of individual drug classes will be discussed in detail.

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