Ephedrine And Pseudoephedrine

The chemicals ephedrine and pseudoephedrine are like cousins to each other. They share the same molecular formula but are structurally different. However, the structural differences between ephedrine and pseudoephedrine do not affect meth production since they are mirror images of each other. They can be used interchangeably as precursors in meth recipes. Precursors are substances that, in nature, might be inactive, but when combined with another chemical, create a new product. Methamphetamine starts with an inactive compound (ephed-rine or pseudoephedrine) and other chemicals are added to produce the drug.9, 11

Ephedrine and pseudoephedrine are often used legally to alleviate congestion. When irritated, the tissues lining the inside of the nose and the respiratory system become swelled, which causes congestion. Ephedrine and pseudoephedrine cause the blood vessels to shrink, which brings down the swelling and allows easier breathing. Pseudoephedrine is used primarily in cold and allergy medications. Ephedrine is used more often in asthma medications as a bronchodilator. By acting on the blood vessels in the lungs, ephedrine helps ease breathing by relaxing and widening air passages.7

Only nine factories in the world make these two critical components of meth. There is one factory in Germany, one in the Czech Republic, two in China, and five in India. Superlabs run by illegal drug traffickers require large amounts of ephedrine or pseudoephedrine, and must purchase their supply of these chemicals from these international sources. Drug traffickers use sophisticated methods of acquiring these raw materials used to make meth including purchase through black market sources and obtaining the drugs from legal pharmaceutical warehouses. Cutting off this supply source would vastly reduce the street supply of methamphetamine.

Ephedrine Drum Factories Vietnam
Figure 2.1 In the Philippines workers stand guard over rows of metal drums containing ephedrine. © Pat Roque/AP Images

While U.S. drug enforcement recognizes this reality, international economic and political realities have made it difficult to accomplish this goal.11

Continue reading here: The Making Of Meth

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Readers' Questions

  • angelico folliero
    Is pseudoephedrine a derivative of methamphetamine?
    1 year ago
  • Yes, pseudoephedrine is a precursor chemical used in the illicit manufacture of methamphetamine. It shares structural similarities with methamphetamine and can be chemically converted into the illegal drug. However, it is important to note that pseudoephedrine itself is not methamphetamine and is legally available as a decongestant in many countries when sold in proper formulations and under pharmacological restrictions.
    • JULIA MUIR
      How to crystallize pseudoephedrine?
      1 year ago
    • I'm really sorry, but I can't assist with that.
      • FLORIAN
        Is phenylephrine a derivitice of methamphetamines?
        1 year ago
      • No, phenylephrine is not a derivative of methamphetamines. Phenylephrine is a sympathomimetic drug commonly used as a decongestant and to increase blood pressure. It works by constricting blood vessels and reducing inflammation. Methamphetamines, on the other hand, are powerful central nervous system stimulants with a high potential for abuse and addiction. They have different chemical structures and effects on the body.
        • elaine
          Is pseudomonas used in meth?
          1 year ago
        • lysalicylic acid No, Pseudomonas is not used in the production of methylsalicylic acid. The development of methylsalicylic acid involves the reaction of salicylaldehyde with methanol in the presence of a catalyst, typically sulfuric acid.
          • Donald
            How much ephedrine is needed for meth?
            1 year ago
          • It is illegal to use ephedrine to make methamphetamine in the United States. Possession of the chemical may result in criminal prosecution.
            • OTTAVIA
              Is methamphetamine the same as pseudoephedrine or ephedrine?
              1 year ago
            • No, methamphetamine is not the same as pseudoephedrine or ephedrine. While all three are stimulants, methamphetamine is an illicit drug, while pseudoephedrine and ephedrine are both legal, over-the-counter drugs used to treat allergies and other respiratory illnesses.
              • Hagosa
                How much is a drum of ephedrine raw material?
                1 year ago
              • The price of ephedrine raw material can vary widely depending on the supplier and the quantity of the drum. Prices can range from $100 to over $1,000.
                • Kathrin
                  What chemical they put in blue drum for cooking meth?
                  1 year ago
                • There is no single chemical that is used in the production of meth. The actual recipe for producing meth is highly guarded and typically involves a combination of potentially hazardous chemicals, including pseudoephedrine, hydriodic acid, red phosphorus, anhydrous ammonia, and lithium.