Agonists And Antagonists

Remember, the primary job of the neurotransmitter is to fit or "lock" into its own particular receptor, and then to initiate specific physiological responses within the body. However, many drugs, such as THC, are able to bind or attach themselves to a specific receptor, thus mimicking or blocking the normal function of the neurotransmitter destined for that receptor. Some drugs are agonists that activate or "turn on" receptors, and some are antagonists that block receptor function. It is not even that straightforward: many receptors in the brain are linked so that activation of one may block the function of another. These linkages are created by a variety of cellular messengers whose function is to relay information from inside neurons or from one neuron to another.

Thus, proper functioning of the nervous system relies on balancing the results of these receptor activations, regardless if the receptor is activated by a drug mimicking or blocking a neurotransmitter or by the specific neurotransmitter itself. This balance is found between the "excitatory" (stimulant) actions of neurotransmitters and the "inhibitory" (depressant) actions of neurotransmitters. As an example, let us look at a drug that acts like an antagonist that blocks the inhibitory action of a neuro-transmitter. This blockade could upset the balance of normal neuronal function by allowing excitatory activity to become the more dominant neuronal action. In a myriad of ways, these types of neuronal imbalances can be translated to the physical and psychological effects that are seen after using drugs such as marijuana. In this manner, we can see that the actions of agonists and antagonists can be quite complex.

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Responses

  • markus blau
    Is marijuana drug an agonist or antagonist?
    2 years ago
  • Gaspare
    Is canbis and agonist or antagonist?
    2 years ago
  • sherry
    What are some antagonists of marijuana?
    2 years ago
  • Menegilda
    What are some medications (agonists/antagonists) for treating Marijuana?
    1 year ago
  • Nebay
    Is ecstasy an agonist or antagonist?
    1 year ago
  • stephen
    What are the cannabis agonists?
    1 year ago
  • hamid
    Is there an antagonist for cannabis?
    1 year ago
  • Melba
    Is marijuana an agonist or antagonist on the neurotransmitter?
    1 year ago
  • Sabrina
    Is weed an agonist or antagonist?
    8 months ago
  • shay
    Is weed an antagonist drug?
    8 months ago
  • elisa
    Is marijana an agonist or antagonist?
    8 months ago
  • niko
    Is peyote an agnosist or antagonists?
    8 months ago
  • katariina
    Why is cannabis an antagonist drug?
    8 months ago
  • guido
    Is cannabis an antagonistic drug?
    7 months ago
  • Paul
    Is cannabis a drug agonist?
    7 months ago
  • gebre
    Is thc a competitive agonist?
    6 months ago
  • bonnie
    Is marijuana an agonisr?
    4 months ago
  • roberto schiavone
    What type of drug is marijuana classified as agonist?
    2 months ago
  • dana baker
    Is cannabis an agonist or antagonist?
    2 months ago
  • kerstin
    Is marijana agonistic?
    2 months ago
  • SHUKORNIA
    Is mrijuana an agonist?
    2 months ago
  • asmarina
    What are some medications (agonists/antagonists) for treating the following drug addictions?
    2 months ago
  • Sisko
    How each of the four basic types of drugs work agonist, antagonist, etc?
    10 days ago

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