The stem bark of Phellodendron amurense Ruprecht (Rutaceae) has long been used in TEM for the treatment of inflammation and fever as a traditional herb medicine having anti-inflammatory, immunostimulatory, and antitumor activities. It contains some alkaloid components such as berberine and worenine. The antioxi-dant, anti-inflammatory, and antityrosinase activities of P. amurense have been studied . Phellodendri can scavenge superoxide radical (O2- ) generated through the hypoxanthine-oxidase system and hydroxyl radical OH generated through the Fenton reaction and can inhibit lipid peroxidation induced by the hydroxyl radical generation system .
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