Multidrug Resistance

Multidrug resistance is a phenomenon that often is associated with enhanced drug efflux and thus decreased intracellular drug accumulation in tumor cells. It often is related to overexpression of P-glycoprotein on the surface of tumor cells, which reduces drug cytotoxicity. Curcumin has been shown to suppress the overexpression of P-glycoprotein in the multidrug-resistant human cervical carcinoma cell lines [38]. Curcumin also down-regulates drug resistance by inhibiting expression of the mdr gene, which is responsible for this phenomenon [39].

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Natural Treatments For Psoriasis

Natural Treatments For Psoriasis

Do You Suffer From the Itching and Scaling of Psoriasis? Or the Chronic Agony of Psoriatic Arthritis? If so you are not ALONE! A whopping three percent of the world’s populations suffer from either condition! An incredible 56 million working hours are lost every year by psoriasis sufferers according to the National Psoriasis Foundation.

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