Gamma Butyrolactone GBL

GBL is also known by the chemical names 2,(3H)-furanone di-hydro, butyrolac-tone, 4-butyrolactone, dihydro-2(3H)-furanone, 4-butanolide, 2(3H)-furanone, di-hydro, tetrahydro-2-furanone, and butyrolactone y [15]. GBL is widely available on the Internet as Verve or Jolt. These are marketed as products that enhance sexual performance. Other GBL product names include Longevity, Revivarant, G.H. Revitalizer, Gamma G, Blue Nitro, Insom-X, Remforce, Firewater, and Invigorate [16].

GBL is a precursor to the compound gamma-hydroxybutyrate (GHB), to which it is rapidly metabolized once ingested. GHB is thought to be a partial agonist at the gamma-aminobutyric acid receptor and can lead to rapid respiratory arrest, hypotension, bradycardia and death. It has been linked to 58 deaths and more than 5700 recorded overdoses [17].

There is no evidence for GBL as a safe and efficacious treatment for ED.

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