Cystic fibrosis, the most common lethal hereditary disease in the white population, is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CFTR mutation disrupts the surface localization and/or gating of the CFTR chloride channel. The most common cystic fibrosis mutant is AF508-CFTR, which inefficiently traffics to the surfaces of most cells. In a recent report, Egan et al. demonstrated that curcumin corrected the cystic fibrosis defects in AF508 cystic fibrosis mice . Most likely, curcumin exerts these effects by directly stimulating the CFTR chloride channels .
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Do You Suffer From the Itching and Scaling of Psoriasis? Or the Chronic Agony of Psoriatic Arthritis? If so you are not ALONE! A whopping three percent of the world’s populations suffer from either condition! An incredible 56 million working hours are lost every year by psoriasis sufferers according to the National Psoriasis Foundation.