The Gallstone Elimination Report
Mild diarrhea and slightly raised serum transaminases are very common with chenodeoxycholic acid, while ursodeoxycholic acid seldom causes significant diarrhea or hypertransaminasemia. This difference is puzzling, since ursodeoxycholic acid, like chenodeoxycholate, is metabolized to lithocholate, and some if not all animal studies have shown evidence of hepatotoxicity. One undesirable property of ursodeoxycholic acid is that occasionally treatment is followed by the development of resistant (and radio opaque) coatings to gallstones, thus retarding or preventing further dissolution. Neither hypersensitivity nor tumor-inducing effects reactions have been reported.
GALLSTONE-SOLUBILIZING DRUGS Gallstone-solubilizing (gallstone-dissolving) drugs, such as ursodiol (Actigall), suppress the manufacture of cholesterol and cholic acid by the liver. The suppression of the manufacture of cholesterol and cholic acid may ultimately result in a decrease in the size of radiolucent gallstones.
Immunoglobulin (Ig) is quite effective against hepatitis A when administered to anyone exposed to the virus as soon as possible or within two weeks after jaundice appears. Vaccines for hepatitis are now a common feature of immunization programs the world over. Treatment for acute hepatitis consists of rest and small, nourishing meals, fluids, and sometimes antinausea drugs such as trimethobenza-mide (Tigan). Chronic cases of hepatitis B and C are treated with interferon. The problem of gallstones is usually solved by surgical operation. Chenodiol, a recently available drug that dissolves gallstones is an alternative to surgery, but troublesome side-effects have been reported.
Uses In Malaysia, a decoction of the leaves is drunk to relieve the bowels of costiveness, heal hemorrhoids, expel gallstone, and to assuage liver discomfort. A paste of the leaves is applied externally to heal cuts, wounds, and ulcers, and to soothe swollen parts. The juice expressed from the plant is used to assuage earache.
Ursodeoxycholic acid (UDCA) is a naturally occurring bile acid that has been used to change the composition of bile in an effort to dissolve gallstones, and in the management of chronic cholestatic disorders. It also has been used as a therapy for intrahepatic cholestasis of pregnancy. Intrahepatic cholestasis of pregnancy is characterized by maternal pruritis with elevated serum bile acids and liver-function test abnormalities, and associated with an increased rate of fetal distress, stillbirth, premature deliveries, and perinatal morbidity. One study reported that only high levels of serum bile acids ( 40 imol l) were associated with increased fetal risks (Glantz 2004). Ursodeoxycholic acid improves pruritis and biochemical abnormalities in
A family history of diabetes are at a higher risk for developing these complications. These serious complications are associated with high blood pressure, heart attacks, strokes, and gallbladder problems. It's not clear if high doses are more likely to cause these problems than low doses. It's not clear if atypical antipsychotics cause these changes in metabolism directly or whether the changes result from weight gain. In either case, it is important to monitor your weight and be tested regularly for the presence of high cholesterol and diabetes. Careful dieting and exercise can minimize weight gain and even permit weight loss in people who have gained weight.
These essential fatty acids were used by Dr. Joanna Budwig (nominated for the Nobel Peace Prize every year since 1979) to successfully treat terminal cancer patients, as well as those suffering from cardiovascular disease, glandular atrophy, gall stones, kidney degeneration, acne, dry skin, menstrual problems and immune deficiency.
The pattern and prognosis of liver injury in children is distinct from that seen in adults, despite some overlap liver disease develops in 40-60 of infants who require long-term parenteral nutrition for intestinal failure (89). The longer parenteral nutrition is used in neonates the greater is the risk of developing cholestasis, and the risk approaches 100 in neonates who receive parenteral nutrition for more than 8 weeks, especially if parenteral nutrition has been started very early in life (83,136). The particularly high risk in infants can be explained by factors that are specific to this age group namely, immaturity of the enzyme systems responsible for hepatic conjugation, disturbance in the physiological patterns of enteral nutrition, and excessive secondary bile acid production and absorption from a contaminated small bowel. The bile of premature and newborn infants differs in its composition from that of adults, and this may account for the differences in solubility (137)....
Methyl-tert-butylether and monoctanoin are solvents that are used for the rapid dissolution of cholesterol gallstones in patients who are not considered suitable for surgery. They are given by direct infusion into the gallbladder (1). However, they are suitable only for cholesterol stones, take too long to act, are often not successful, and have high rates of adverse effects (2). The results of contact dissolution of gallstones using infusions of methyl-tert-butylether by percutaneous trans-hepatic gallbladder puncture have been assessed in 803 patients (3). Stones were dissolved in 724 of 761 patients in whom gallbladder puncture was successful. The 30-day mortality was 0.4 . Common complications were biliary leak, fever, leukocytosis, abdominal pain, and mild increases in transaminases. Toxic effects due to ether were not reported.
Effects Contains cineole, a mild central nervous system stimulant, which may account for its reputation in Arab cultures as a male aphrodisiac. Cineole also kills bacteria that cause bad breath, and cardamom has been used to treat asthma, emphysema, gas, heartburn, acid indigestion, laryngitis, and vaginitis. Cardamom also contains the compound borneol, which is helpful in treating gallstones.
All atypical antipsychotics can cause substantial weight gain (an increase of 10 to 20 of your current body weight in the first couple of months), diabetes, and elevations of cholesterol or triglycerides (another form of fat in the blood). People with a family history of diabetes are at a higher risk for developing these complications. These serious complications are associated with high blood pressure, heart attacks, strokes, and gallbladder problems. It's not clear if high doses are more likely to cause these problems than low doses. It's not clear if atypical antipsychotics cause these changes in metabolism directly or whether the changes result from weight gain. In either case, it is important to monitor your weight and be tested regularly for the presence of high cholesterol and diabetes. Careful dieting and exercise can minimize weight gain and even permit weight loss in people who have gained weight.
This drug has been used since the 1930s for easing pain in many conditions, including migraine headaches, surgery, gallbladder attack, sickle cell anemia crisis, childbirth, and emergency treatment of injury on mountaineering expeditions. The drug is also used to manage porphyria, a body chemistry disorder that can make a person extremely sensitive to light and that can include violent outbursts. The substance is used to bring persons out of a PCP psychosis. Experimental usage of meperidine and dextroamphetamine together has reduced symptoms of mental depression, but the test was too brief to measure how long benefits might continue. Oral meperidine dosage can partly numb a person's mucous membranes, and the drug is used as one element of general and local anesthesia. The substance has a calming action but is not considered to be a sleep inducer at medical dosage levels. Upon prolonged usage the calming action can be replaced by depression and uneasiness. Depending on specifics...
Effects Caffeine is one of the most powerful legal stimulants it gives a mental boost by releasing adrenaline and noradrenaline into the bloodstream. It interferes on a cellular level with the compound adenosine, in effect flatlining the body's state of arousal, allowing the body to shift into high gear. It may also affect dopamine, acetylcholine, and other neurotransmitters. All coffee, including decaffeinated, contains at least three compounds that act like opiates, or heroin, on the brain. It improves typing skills, mental alertness, energy, reaction time, concentration, and accuracy in performing tasks, and relieves fatigue, mainly by causing the release of norepinephrine in the brain. It improves physical endurance by stimulating the skeletal muscles, increases the production of stomach acid and urine, causes bowel movements, and dilates the bronchial tubes (making it easier to breathe). According to studies, it has no effect on memory or clarity of thought. In addition, the...
Bear bile contains bile acids, cholesterol, and phospholipids (phosphatidylcholine, phosphatidylethanolamine, and phos-phatidylinositol). It has been used for centuries in traditional Chinese medicine to treat liver and eye complaints and convulsions, and, in combination with curcuma and capil-laris, gallstones and cholecystitis. More recently it has been touted as a treatment for stroke on the basis of animal experiments. It has few or no adverse effects, but by the same token probably has little or no efficacy, although it does contain ursodeoxycholic acid, which in purified form is effective in managing gallstones.
Greater celandine was traditionally used to improve eyesight and in modern times has been used as a mild sedative, and antispasmodic in the treatment of bronchitis, whooping cough, asthma, jaundice, gallstones, and gallbladder pain. The latex is used topically to treat warts, ringworm, and corns. A semisynthetic thiophosphate derivative of alkaloids from C. majus, called Ukrain, has cyto-toxic and cytostatic effects on tumor cells (1).
Effects Magnesium provides energy aids in the metabolism of calcium and vitamin C enhances the immune system plays a key role in the chemical reactions of some 325 essential enzymes plays a role in the manufacture of DNA and RNA coding in cells and contributes to the formation and growth of cell membranes, nerves, muscles, and the heart. It protects against anxiety, calcium buildup in neurons (a common condition found in those with Alzheimer's), depression, diabetes, fatigue, insomnia (when combined with calcium), kidney stones and gallstones, poor memory, migraines, osteoporosis, heart disease, high blood pressure, tooth decay, the toxic effects of the heart drug digitalis, and in women the tension of PMS and postmenopausal bone loss. Most people may not get enough, and athletes should be especially aware of their intake, as exercise depletes the body of this nutrient. In combination with vitamins C and E and choline, it may prevent some of the side effects of vitamin A and D...