De Stefani E, etal. (1996) Canc EpidBiom Prev 5(7): 515-519.

Guggliucci A, et al. (1995) Biochem Mol Biol Int 35(1): 47-56.

Guggliucci A, etal. (1996) Biochem Biophys Res Com 224(2): 338-344.

Haraguchi H, etal. (1999) PhytotherRes 13(2): 151-156.

KashiwadaY, etal. (1993) J Nat Prod 56(12): 2077-2082.

Leitao AC, etal. (1994) Braz J Med Biol Res 27(7): 1517-1525.

Mucillo-Baisch AL, etal. (1998) J Ethnopharmacol 60(2): 133-139.

Nishimura K, etal. (1999) J Nat Prod 62(8): 1128-1133.

Xu C, etal. (2004) J Ethnopharmacol 91(2-3): 345-349.

Warning: Caution must be taken as the toxic effects of this plant are unknown. Note that Mate solutions, which have become popular for their antioxi-dant/antiradical properties, are however mutagen in the Ames test (TA97, TA98, TA100, TA102 strains, 20mg/plates to 50mg/plates) and genotoxic (WP2s strain; Leitao AC et al., 1994) showing that antioxidant/antiradical natural products can be noxious. Furthermore, a case-control study which includes 497 cases of lung cancer and the same number of controls, reveals that mate is associated with risks of upperaerodigestive tract cancer (De Stefani E etal., 1996). A case-control study involving interviews with 111 incident cases and 222 controls shows a high mortality rate for bladder cancer, on account of black tobacco smoking and mate ingestion (De Stefani E et al., 1991). The case of a young woman who developed a veino-occlusive disease after drinking mate over a number of years is reported by Mc Gee et al. (1976).

The Smoker's Sanctuary

The Smoker's Sanctuary

Save Your Lungs And Never Have To Spend A Single Cent Of Ciggies Ever Again. According to a recent report from the U.S. government. Centers for Disease Control and Prevention, more than twenty percent of male and female adults in the U.S. smoke cigarettes, while more than eighty percent of them light up a cigarette daily.

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