References

Akbarsha MA, et al. (1990) Ind J Exp Bull 28(5): 421-426.

Burgos RA, et al. (1997) J Ethnopharmacol 58(3): 219-224.

Chang RS, etal. (1991) Proc Soc Exp Biol Med 197(1): 59-66.

Choudhury BR, etal. (1984) Method Fid Exp Clin Pharmacol 6(9): 481-485.

Choudhury BR, etal. (1985) Methods Find Exp Clin Pharmacol 7(12): 617-621.

Go Z, et al. (1996) J Tongji Med Univ 16(4): 193-197.

Gupta S, etal. (1990) IntJCrude Drug Res 28(4): 273-283.

Handa SS, et al. (1990) India J Med Res 92: 284-292.

Zhao YH, etal. (1991) Chin Med J Engl 104(9): 770-775.

Zhang CY, etal. (1991) Clin Exp Pharmacol Physiol 23(8): 675-678.

Zoha MS, etal. (1989) Bangl Med Res Counc Bull 15(1): 34-37.

Warning: A sun-dried powder of Andrographis paniculata Nees mixed with the food (2g/Kg/day) given to female mice for a duration of 6 weeks, inhibits all the pregnancies when mated with fertile males, which did not receive the plant (Zoha MS et al., 1989). Dry leaves powder given per os to albino rat males (20 mg/day) for 60 days, abrogates spermatogenesis and induces degenerative changes in seminiferous tubules, regression in Leydig cells and epididymis (Akbarsha MA et al., 1990). Note that an testicular toxicity on male rats was reported in another publication (Burgos RA et al., 1997).

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