Anazetti MC, et al. (2003) Toxicology 188(2-3): 261-274. Farias RA, etal. (1997) Planta Med 63(6): 558-560. Peres MT, et al. (1997) J Ethnopharmacol 56(3): 223-226. Piaciente S, etal. (1998) J Nat Prod 61(3): 318-322.



Warning: The toxic principles of croton oil consist of phorbol esters diterpenes which cause intense inflammation by contact with the skin and promote the development of tumors. The oil expressed from the seeds of a number of plants classified within the genus Croton or croton oil is probably the most drastic and most irritating of all existing purgatives.

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