Pharmaceutical interest

Dietetic properties: The seeds of Parkia speciosa Hassk contain several antibacterial cyclic polysulphides which are responsible for the pungent flavor (Gmelin et al., 1981). The plant is known to contain thiazolidine-4-carboxylic acid, which protects the liver against toxic agents. It is also antiageing and an effective nitrite-trapping agent that

inhibits the formation of carcinogenic N-nitroso compounds (Susilo et al., 1982). Stigmast-4-en-3-one characterized from a chloroform extract of the empty pods lowers glucose levels in alloxan-induced diabetic rats confirming thereby the antidiabetes property of the plant (Jamaluddin F et al, 1995). The exact pharmacological mechanism of action of stigmast-4-en-3-one remains unknown, but a glucocorticoid-like mechanism is possible. Note that stigmast-4-en-3-one probably has hyperc-holesterolaemic properties as well.

Uses: In Indonesia and Malaysia, the seeds of Parkia speciosa Hassk. are eaten raw to treat diabetes and liver discomfort, and to expel intestinal worms. The seeds cause smelly urination when ingested.

Stigmast-4-en-3-one

COOH

Stigmast-4-en-3-one

Thiazolidine-4-carboxylic acid

Continue reading here: Family Caesalpiniaceae R Brown in Flinders 1814 nom conserv the Caesalpinia Family

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