Pharmaceutical interest

Rottlerin: The dyeing principles of kamala powder are phloroglucinol derivatives: rottlerin (mallotoxin) and isorottlerin. Aqueous and ethanolic extracts of leaves of Mallotus philippensis (Lamk.) Muell. Arg. inhibit the spontaneous mobility of Setaria cervie microfilariae with an LC50 value of 18ng/mL and LC90: 20ng/mL (Singh R et al., 1997). This property is most probably due to the presence of rottlerin, which is known to destroy intestinal worms efficiently, possibly through inhibition of calmodulin-dependent protein kinase III (Parmer TG et al., 1997) that phosphorylates a number of substrates that regulate the proliferation of cells upon mitogen stimulation.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

Get My Free Ebook

Post a comment