Pharmaceutical interest

L-Methionine sulphoximine: A common poison found in the Connaraceae and probably in Rourea minor (Gaertn.) Leenh. is L-methionine sulphoximine which (Jeannoda VL et a/., 1985). The mode of action of L-Methionine sulphoximine is based on the fact that it is shaped like L-glutamic acid (an excitatory amino acid) and acts as a false substrate for glutamine synthetase, which normally converts glutamic acid into glutamine. Glutamic acid accumulates in neurons and causes a continuous depolarization of dendrites, hence resulting in central nervous system disturbances and convulsions. L-Methionine sulphoximine lowers extracellular potassium during acute hyperammonaemia (Sugimoto H etal., 1997).

Uses: In Malaysia, a decoction of the roots is drunk to treat fever, and the pounded roots are drunk to heal sores. In the Philippines, a decoction of the roots is used to invigorate the uterus, expel impurities, induce vomit and to kill wild dogs.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

Get My Free Ebook

Post a comment