Pharmaceutical interest

Anti-inflammatory property: The juice given orally at a dose of 4mL/Kg, protects guinea-pigs from death by asphyxia caused by 5 mg of histamine suggesting an anti-histaminic effect (Nassis CS et al., 1992). Kalanchoe pinnata Pers. inhibits T-cell-mediated responses such as the mixed leukocyte reaction and the delayed type hypersensitivity reaction on account of the fatty acid mixtures of palmitic acid, stearic acid of arachidonic and behenic acids (MoraesVL etal., 2000).

Other properties: An extract of leaves given orally at 8 mg per day protects Fi9-148- (a) ^an^â„¢pinnas (i_ami<.) pers.

Uses: Kalanchoe pinnata (Lamk.) Pers. is counter-irritant. In Malaysia, the juice expressed from this plant is mixed with honey and used to treat tonsillitis, mastitis, earache, inflammation and haemoptysis. In India, the bark is used to stop diarrhea, flatulence and vomiting, assuage pain and to counteract snake-and scorpion-poisoning. The leaves are applied externally to heal wounds and boils, and the plant is used to treat jaundice.In Cambodia, Laos, and Vietnam, a paste made from the powdered leaves is used to heal burns and to soothe scalds.

BALB/c mice against Leishmania amazonensis (Da Silva SAG et al., 1995). Bufadienolides of Kalanchoe pinnata (Lamk.) Pers. inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced early expression of the Epstein-Barr Virus by Raji cells (Supratman U et al., 2001). The hepatopro-tective property of Kalanchoe pinnata (Lamk.) Pers. is confirmed as the juice of the leaves protects rats against carbon tetrachloride-induced hepatotoxicity (Yadav NP et al, 2003).

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