Pharmaceutical interest

Chemotherapeuticproperties: The antiseptic property of Argemone mexicana L. is very likely to be attributed to iso-quinoline alkaloids such as sanguinar-ine, berberine and protopine, which abound in the plant (Santos AC etal, 1932). Sanguinarine exhibits a broad

Fig. 43. Argemone mexicana L. From: Delhi University Herbarium 004344. Flora of India. Geographical localization: Delhi ridge, Delhi, India, altitude 720ft., Feb 1961. Field Collector: SK Avova. Botanical identification: CS Venktast.

petals which are yellow and mem-single-celled and contains numerous

Uses: In Burma, the latex of Argemone mexicana L. is used to treat dropsy and the seeds are eaten to relieve the bowels of costiveness. In China, the leaves of Argemone mexicana L. are used to invigorate health, inhibit fertility and promote digestion. In Indonesia, Argemone mexicana L. is used to treat jaundice, skin affections, dropsy, blisters and ulcers, and to promote menses. In the Philippines, the flowers are used to induce narcosis and treat lung diseases.

panel of pharmacological activities. It is antimicrobial, antifungal, and anti-inflammatory. It inhibits Na+/K+-dependent ATPases, has a positive inotropic action, and interacts with DNA. Sanguinarine chloride is used in mouthwashes for its ability to bind dental plaque and to inhibit the growth of bacteria at a very low dose. The plant is interesting because of (+/-)-6-acetonyldihydrochelerythrine, which exhibits a significant Anti-Human Immunodeficiency Virus activity in H9 lymphocytes with EC50 and Therapeutic Index values of 1.77 ^g/mL and 14.6, respectively (Chang YC et al, 2003). The acetone fraction of the petroleum ether extract of seeds from Argemone mexicana L. destroys the larvae of Aedes aegypti at doses of 200, 100, 50 and 25ppm (Sakthivadivel M et al., 2003). The plant displays some levels of antiplasmodial activities (Adjobimey T et al., 2004).

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