Pereskia bleo DC
[After the French astronomer Nicolas Claude Fabri de Peiresc (15801637) and from a local South American, bleo = Pereskia bleo DC]
Physical description: It is a spiny shrub which grows to a height of 28 m. It is native to South America and cultivated in several tropical countries for decorative and medicinal purposes. Leaves: simple, spiral, glossy and succulent. The petiole is 3 cm long. The blade is lanceolate and 6cm-20cm x 2cm-7cm. The areoles produce 05, 5mm-1 cm long spines on young stems, and up to 40, 2 cm long spines for older stems. The flowers are 4cm-6cm, red or orange, terminal, grouped by 2-4 and showy. The fruits are 4cm-5cm in diameter, fleshy and glossy conical berries containing 6mm-8mm diameter seeds (Fig. 59).
Common name: Wax rose.
Uses: In Malaysia, Pereskia bleo is used internally to treat cancer.
Pharmaceutical interest: There is an expanding body of evidence to suggest that Perecksia species are of chemotherapeutic value. A methano-lic extract of Pereskia bleo DC induce apoptosis in breast carcinoma, T47-D cell line (Tan ML et al., 2005) and a
methanol extract of Pereskia corrugata inhibits the growth of T-47D human breast carcinoma cell line cultured in vitro with an EC50 value below 2 ^g/mL and induces apoptosis, via activation of caspase-3 and c-myc pathway (Lan MT etal, 2001). What are the principles involved here? Polysaccharides, flavonoid glycosides?
Continue reading here: Family Chenopodiaceae Ventenat 1799 nom conserv the Goosefoot Family
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