The somadendritic region of most neurons is accessible for electrophysiological studies. In contrast, direct electrophysiological recording from axon terminals of mammals is either impossible or extremely difficult. Accordingly, we know relatively well how cannabinoids change the function of ion channels in the somaden-dritic region. Our knowledge on electrophysiological changes in axon terminals is limited; we can only assume that ion channels are influenced similarly as in the somadendritic region. In this section, effects on the somadendritic region are dealt with.
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