Instead of just Treating Diseases

In Section I of this manual several basic aspects relevant to the pharmacological treatment of mental disorders - such as influencing factors, prescribing practices and ethical issues, the role of pharmacotherapy at different levels of the health system and evaluation of pharmacotherapy in psychiatry are reviewed and discussed. Section II presents some basic principles for rational prescribing, and of pharmacokinetics relevant to a more efficient utilization of medicine. In Section III, all the...

Treatment should have the shortest possible duration

The above elements are certainly helpful for the establishment of principles for good treatment and rational prescribing as well More specifically, the following, adapted from Ghodse & Khan (6), are indicated as additional principles for the rational prescribing of psychoactive medication L There should be a clear target symptom or symptoms that the medicine is known to affect, e.g., depressive mood, thought disorder, anxiety, restlessness, insomnia or the like, 2. The dosage should be...

Are prescribed at the same time

In psychiatry non-compliance is made more problematic by the reduced insight accompanying many mental disorders. The lack of adequate insight, especially in psychotic disorders, can act as an important obstacle for the patient in understanding the need for a regular, careful compliance with the drug treatment administered. Among factors affecting compliance, an important one is the complexity of the drug regime. Several studies have found that, if three or more medicines are being prescribed...

Essential Drugs In Psychiatry

Bertolote G, de Girolamo (Editors) This document describes the use of essential drugs for the treatment of people with mental disorders, following the WHO List of Essential Drugs. it is the second in a series of four issues. The first one introduced the concept of essential treatments the following two issues will deal with psychological and social essential interventions, respectively. This document is part of WHO's Initiative of Support to People Disabled by Mental Illness. Key-words...

Prophylactic Use of Anticholinergics in Patients on Long Term Neuroleptic Treatment a Consensus Statement u

The heads of centres collaborating with the WHO in biological research on mental disorders decided to develop a series of consensus statements on key issues in biological research and treatment of psychiatric problems. The statement on prophylactic use of anticholinergics in patients on neuroleptic treatment is the second of the proposed series. Anticholinergics (that is, agents which antagonise the action of acetylcholine at muscarinic receptor sites) are not only commonly used for the...

Temazepam

Temazepam is a benzodiazepine with anxiolytic and hypnotic properties. It is metabolized in the liver to several inactive metabolites, which are mainly excreted in the urine as glucuronides. The drug response becomes evident 30-90 minutes after oral administration. The plasma half-life is 6-8 hours, although some recent studies seem to show that the half-life may be longer, about 15 hours. Temazepam should be stored in tightly closed containers protected from light. Temazepam, although a...

Tables of equivalency of selected psychiatric drugs

EQUIVALENCY OF SELECTED ANTISFYCHOTIC DRUGS TABLE 1. EQUIVALENCY OF SELECTED ANTISFYCHOTIC DRUGS TABLE 2. COMPARATIVE FEATURES OF THREE ANTIPSYCHOTIC DRUGS TABLE 2. COMPARATIVE FEATURES OF THREE ANTIPSYCHOTIC DRUGS TABLE 3. EQUIVALENT AVERAGE DOSES OF SELECTED ANTIDEPRESSANT DRUGS TABLE 3. EQUIVALENT AVERAGE DOSES OF SELECTED ANTIDEPRESSANT DRUGS TABLE 4. THERAPEUTIC AVERAGE DOSES OF SELECTED BENZODIAZEPINES TABLE 4. THERAPEUTIC AVERAGE DOSES OF SELECTED BENZODIAZEPINES TABLE 5,...