Promising Theoretical Methods
Strike and others' favorite pastime is to comb the library for new methods. Even though we have so many proven, high-yielding methods available (see this entire book), there is always room for more. Relentlessness drives us to find even cheaper, higher yielding methods. But the biggest reason is to make a buffer zone of so many options that governmental restriction is rendered useless. That is our power. So many committed, dangerously-intelligent people around the world with far more motivation than any bureaucratic agency will ever hope to have.
You're not going to find journal articles with new syntheses written especially for X or speed anymore. The scientists of the world already have recipes that work and the access to the restricted chemicals necessary to make them work. So why should they look for anything new? They don't. There is no reason for them to do so.
But we have many reasons. That is why the people of the underground are actually progressing the fields of carbonyl, amine and amphetamine science. Believe it or not, the novel applications of journal methods on precursors such as ours are on equal par with published research work. Half of the stuff in this book is publish-able, proper science done by people with no funding. It is actually amazing when you think about it.
So like Strike was saying, without any new, direct literature synthesis of amphetamines, we are forced to take ideas from work on molecules that are similar to our own. Often molecules that one would not think have any relationship at all.
For molecules similar to safrole or allylbenzene we take the work done on any terminal alkene such as 1-heptene, 1 octene. Another term to look for is 'olefin' which is a term for a doublebond containing species. What we then look for are articles about these olefins where the functional groups we are looking for are formed. Articles with terminology like 'methyl ketones from' (P2P), 'ketones from', 'amines from' etc. Or when we want to see about new ways to aminate a ketone (make final product from P2P) we look for any article about ketones where amines are formed. Sound like science fiction to you? Well, how do you think we came up with half the recipes in this book!? It works!
Every article such as these may have the potential to be useful. But it takes a lot of looking, a keen eye and a sense for what is real. The contributions in this section are just that (real). These have gone through the right channels and are contributed by the same chemists that brought you the rest of this book. These are considered to have the greatest potential and are here for your consideration to use in legal research of your choice. Be warned, though. The chemistry here is a little hairy and, for the sake of time and Strike's sanity, is not explained as simply as the other recipes in this book.
Continue reading here: Phenylacetones
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