Piperonal or Benzaldehyde From Chloromethyl Intermediate

The benzylchloride compound made in the previous recipe can be converted to piperonal or benzaldehyde using a chemical called hexamine [137 p817, 37 p700, 136]. Hexamine, also known as methenamine or hexamethylenetetramine, is a weird looking chemical that is easily made from formaldehyde but is better off being purchased.

Piperonyl chloride

Piperonal

Piperonyl chloride

Piperonal

In a flask with stirring is added 158g piperonyl chloride or 126g -241 -

benzyl chloride, 140g hexamine and either 500mL 50% aqueous acetic acid or 500mL 60% aqueous ethanol. The solution is re-fluxed for 2 hours, then 200mL 3N HCI is added and refluxing is continued for 15 minutes more. When cool, the solution is extracted with ether, the ether washed 3 times with water, dried through Na2S04 and vacuum distilled to afford piperonal or ben-zaldehyde (yield=70%). The two products are quite fragrant which will give the chemist an idea of the success of the procedure. Did you know that a lot of methylamine is produced as a side product of this reaction? How it can be salvaged Strike has no idea.

Was this article helpful?

0 0
Aromatherapy Natural Scents that Help and Heal

Aromatherapy Natural Scents that Help and Heal

You have probably heard the term Aromatherapy and wondered what exactly that funny word, „aromatherapy‟ actually means. It is the use of plant oils in there most essential form to promote both mental and physical well being. The use of the word aroma implies the process of inhaling the scents from these oils into your lungs for therapeutic benefit.

Get My Free Ebook


Post a comment