Contraindications Precautions And Interactions

The topical enzyme preparations are contraindicated in patients with known hypersensitivity to the drugs, in wounds in contact with major body cavities or where nerves are exposed, and in fungating neoplastic ulcers. These drugs are Pregnancy Category B drugs and are used cautiously during pregnancy and lactation. Enzymatic activity may be impaired when these agents are administered with several detergents and antiseptics (benzalkonium chloride, hexachlorophene, iodine, and nitrofurazone).

KERATOLYTICS

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