Amitava Dasgupta

Summary

Persons abusing drugs attempt to adulterate urine specimens in order to beat drug testing. Dilution of urine in vivo by consuming excess fluid and various detoxifying agents available through the Internet is a common practice. Household chemicals such as bleach, acid, table salt, laundry detergent, toilet-bowl cleaner, vinegar, lemon juice, and Visine® (Pfizer) eye drops are also used for adulterating urine specimens. Most of these adulterants except Visine eye drops can be detected by routine specimen integrity tests (creatinine, pH, temperature, and specific gravity). However, certain adulterants, such as Klear™, Whizzies, Urine Luck™, and Stealth™, cannot be detected by using routine specimen integrity testing. These adulterants can successfully mask drug testing if the concentrations of certain abused drugs are moderate. Several spot tests have been described in the literature to detect the presence of such adulterants in urine. More recently, urine dipsticks are commercially available (AdultaCheck® 4 [Sciteck], Adulta-Check 6, Intect® 7 [Branan Medical Corporation]) for detecting the presence of such adulterants along with creatinine, pH, and specific gravity. Hair and saliva testing for abused drugs are gaining popularity because such specimens are collected directly from a person. Moreover, abused drugs can be detected for a longer time in hair. Recently, certain hair shampoo and saliva cleaning products have become available to beat drug testing involving hair or saliva specimens.

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