The Lily botanical family Liliaceae

The Lily botanical family (Liliaceae Adans., Juss.) (Table 14) is spread worldwide and contains more than 200 genera and around 3500 species. Some genera of this family produce L-tyrosine-derived alkaloids. The genus Kreysigia yields autumnaline, floramultine and kreysigine.

The genus Colchicum (Colchicum L.) produces colchicine. Stereoidal alkaloids in this family are found in the Hellebore genus (Veratrum Bernch.). Jervine, cyclopamine (Figure 18), cycloposine, protoveratrine A and protover-atrine B yield Veratrum album. O-acetyljervine has been reported in the false hellebore (Veratrum lobelianum Bernch.)136. Four new steroid alkaloids (puqie-nine A, puqienine B, N-demethylpuqietinone, puqietinonoside) have been isolated from Fritillaria species by Jiang et al.171 The bulbs of these plants have been used as an antitussive and expectorant in folk Chinese medicine. All four new alkaloids have been reported to display the antitussive activity on

mouse171.

Table 14 General botanical characteristics of the Lily family

312.313.316

Botanical Forms and Parts

Characteristics

Botanical forms

Herbs

Shrubs

Trees

Climbers (rarely)

Some typical genera

Colchicum

Erythronium

Fritillaria

Gagea

Kreysigia

Lilium

Medeola

Tulipa

Veratrum

Special characteristics

Cosmopolitan family Usually bulbs

Alternate Parallel-weined

Regular

Solitary or in racemes, panicles or umbels

Leaves

Flowers

Fruits

Dehiscent capsule or a berry

Small embryo Albumen

Seeds

Jervine

Jervine

CH3 H

Cyclopamine

CH3 H

Cyclopamine

Hs^CS

Hs^CS

Structure Protoveratrine

HO O

COOCH3

Protoveratrine

Figure 18. Jervine, cyclopamine and protoveratrine structures.

HO O

COOCH3

Protoveratrine

Figure 18. Jervine, cyclopamine and protoveratrine structures.

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