Imidazole alkaloids

This group of alkaloids is an exception in the transformation process of structures, because the imidazole nucleus is already made at the stage of the precursor. The a of these alkaloids is L-histidine, and the first A is developed in a decarboxylation process by histidine decarboxylase (HDC). The histamine is a product of

/V-methyl-A1-pyrrolinium cation

/V-methyl-A1-pyrrolinium cation

Pilosine Structure
Figure 57. Structural development of tropane alkaloids.

this reaction (Figure 58). Other alkaloids from this group include, for example, dolichotheline, pilocarpine and pilosine.

Continue reading here: Quinazoline alkaloids

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