Methyl1 2Hbenzodiazepine14 one2

Fludiazepam.

Chloral hydrate C2H3Cl3O2, Molecular weight 165.42. First synthesized in 1832 but was not introduced into medicine until 1869, when Mathias E.O. Liebreich discovered its effectiveness in inducing sleep. Chloral hydrate acts as a depressant on the central nervous system, with sedative effects similar to those of barbiturates. A therapeutic dose (500 mg to 1 g) produces a deep sleep lasting four to eight hours with few aftereffects, but habitual use of the drug results in addiction. Symptoms of overdose may include deep stupor, dilation of blood vessels, fall in blood pressure and body temperature, and slowed respiration. In a severe overdose, death usually occurs within 5 to 10 hours.

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