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Uses. Nandrolone is used to treat breast cancer and anemia, and the drug has improved asthma and Sjogren's syndrome, a disease that destroys salivary, sweat, and tear glands. Healing action on cornea afflictions has been observed, and rat experiments have explored nandrolone's potential for speeding recovery from tooth extractions. A skin cream containing nandrolone is used against eczema. Human research indicates that the drug can improve osteoporosis, a disease causing brittle bones, although results conflict on how long the improvement lasts. Among some diabetics with a kidney condition called Kimmelstiel-Wilson syndrome, nandrolone has helped both renal and eyesight difficulties. In kidney dialysis, patients' experimental use of nandrolone was able to improve weariness, increase muscle mass, and fight malnutrition. The compound has helped AIDS (acquired immunodeficiency syndrome) patients build up weight, muscles, and strength. The substance has also been given in hopes of stimulating appetite in malnourished cancer patients, although animal cancer research indicates that any weight gain may simply be due to water retention rather than improved nutrition (in contrast to research with healthy animals that produced weight increase associated with protein gain—some livestock raisers illegally dose animals with nandro-lone to promote growth). After administration of the drug, improvement occurred in a case of anorexia nervosa, a psychological condition in which people with normal or low weight misperceive themselves as fat.
Drawbacks. Typically, but not always, studies of humans who use nandrolone have measured declines in cholesterol levels (including HDL, the so-called good cholesterol) and elevation of triglycerides (associated with body processes leading to heart attack and stroke). In monkeys, coronary artery
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