Pregnancy Category None

Uses. This substance has been used for decades. It has similarities to DMT in chemistry and actions and was made a Schedule I substance partly because some AET effects are reminiscent of MDMA. As a Schedule I substance AET has no approved medical use in the United States but has been used elsewhere (in Europe, for example) as an antidepressant.

Intoxication symptoms can resemble those of amphetamine, and urine tests for amphetamine can also pick up AET. When AET was given to rats, in some ways they responded as if they had received either amphetamine or MDMA.

A researcher who used AET reported enjoyable sensations of energy and contentment. As dosage increased, so did euphoria and enjoyment of sensual activity such as eating, music, and sex. In several accounts of effects hallucinations were not reported.

Drawbacks. AET has been associated with agranulocytosis, a blood disease involving development of sores in various places throughout the body.

Abuse factors. Tolerance is reported. Some opiate abusers trying to break their addiction have used AET to ease opiate withdrawal symptoms.

Drug interactions. AET is a monoamine oxidase inhibitor (MAOI), a type of drug that can interact dangerously with some of the other drugs described in this book.

Cancer. Not enough scientific information to report.

Pregnancy. Not enough scientific information to report.

Additional scientific information may be found in:

Daldrup, T., et al. "Etryptamine, a New Designer Drug with a Fatal Effect." Zeitschrift fur Rechtsmedizin 97 (1986): 61-68 (article in German, but summary available in English).

Huang, X.M., M.P. Johnson, and D.E. Nichols. "Reduction in Brain Serotonin Markers by Alpha-Ethyltryptamine (Monase)." European Journal of Pharmacology 200 (1991): 187-90.

Krebs, K.M., and M.A. Geyer. "Behavioral Characterization of Alpha-Ethyltryptamine, a Tryptamine Derivative with MDMA-Like Properties in Rats." Psychopharma-cology (Berlin) 113 (1993): 284-87.

Morano, R.A., et al. "Fatal Intoxication Involving Etryptamine." Journal of Forensic Sciences 38 (1993): 721-25.

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