posure to glutethimide exhibit abnormal behavior, but their own offspring behave normally. Pregnant women have routinely received glutethimide for insomnia, nausea, and vomiting. Humans with sufficient fetal exposure may be born dependent on the drug. It has been used to ease labor. Nursing mothers who take the drug may have enough glutethimide in their milk to make their infants sleepy.
Additional scientific information may be found in:
Bender, F.H., J.V. Cooper, and R. Dreyfus. "Fatalities Associated with an Acute Overdose of Glutethimide (Doriden) and Codeine." Veterinary and Human Toxicology 30 (1988): 332-33.
DiGiacomo, J.N., and C.L. King. "Codeine and Glutethimide Addiction." International
Journal of the Addictions 5 (1970): 279-85. Haas, D.C., and A. Marasigan. "Neurological Effects of Glutethimide." Journal of Neurology, Neurosurgery, and Psychiatry 31 (1968): 561-64 Jones, A.H., and J.F. Mayberry. "Chronic Glutethimide Abuse." British Journal of Clinical
Practice 40 (1986): 213. Kovacs, T. "[Acute Toxicological Cases during a Ten-Year Period in Our Clinic]." Orvosi
Hetilap [Hungarian Medical Journal] 143 (2002): 71-76. Abstract in English. Mould, G.P., S.H. Curry, and T.B. Binns. "Interaction of Glutethimide and Phenobarbital with Ethanol in Man." Journal of Pharmacy and Pharmacology 24 (1972): 89499.
Reveri, M., S.P. Pyati, and R.S. Pildes. "Neonatal Withdrawal Symptoms Associated with Glutethimide (Doriden) Addiction in the Mother during Pregnancy." Clinical Pediatrics 16 (1977): 424-25. Shamoian, C.A. "Codeine and Glutethimide; Euphoretic, Addicting Combination." New York State Journal of Medicine 75 (1975): 97-99.
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