Oxandrolone

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Pronunciation: ok-SAN-droh-lohn

Chemical Abstracts Service Registry Number: 53-39-4

Formal Names: Anatrophill, Anavar, Lipidex, Lonavar, Oxandrin, Provitar, Vaso-rome

Type: Anabolic steroid. See page 24 Federal Schedule Listing: Schedule III (DEA no. 4000) USA Availability: Prescription Pregnancy Category: X

Uses. This drug is used to encourage return of adequate heaviness in persons who have lost too much weight from illness, injury, or medical therapy. Experiments with AIDS (acquired immunodeficiency syndrome) patients measured substantial improvement in weight and strength. Oxandrolone may diminish pain from a bone disease called osteoporosis, although the drug has potential for worsening the underlying bone affliction. In rats and in humans the drug has hastened healing of wounds. Experimental therapy using oxan-drolone against Duchenne muscular dystrophy has been successful.

Drawbacks. Nausea and diarrhea are among the less serious reports of unwanted effects. The substance can masculinize female users and interfere with menstrual periods. In immature rats oxandrolone has drastically interfered with the male reproductive system, a finding that may be relevant to young athletes using the compound without medical supervision. In humans the substance can promote prostate disease and should be avoided by men with breast cancer and generally by anyone with kidney disease (although doctors sometimes give oxandrolone to dialysis patients). The drug has been used to treat hepatitis in alcoholics despite its ability to interfere with bile flow and to cause jaundice or liver malfunction. Fluid retention can occur and be a serious problem for heart patients. Other unwanted effects may include overall higher cholesterol levels (accompanied by reduction of the HDL "good cholesterol"), although unlike some other drugs of this type, oxandrolone has been seen to reduce levels of triglycerides (which are associated with increased risk of heart attack and stroke), and in some cases oxandrolone reduced overall cholesterol as well. Such effects may, however, depend upon what causes the original levels. Oxandrolone can bring about premature bone maturation in children, preventing attainment of normal adult height. Nonetheless, the

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